Khorana Prize Lecture: Professor Sir Shankar Balasubramanian
The Department of Natural Sciences, Manchester Metropolitan University, is delighted to host Professor Sir Shankar Balasubramanian for his Khorana Prize lecture.
Date
29 April 2026
Location
Manchester, United Kingdom
The Department of Natural Sciences, Manchester Metropolitan University are delighted to be hosting Professor Sir Shankar Balasubramanian from the University of Cambridge for his Khorana Prize talk on the 29th April 2026.
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Abstract
"The structure and function of G-quadruplex DNA"
DNA can exist in folded structures that are distinct from the B-DNA double helix. One such structure is the four-stranded G-quadruplex, which can form in certain G-rich sequences. Over the past 25 years or so, our lab has been seeking to understand the nature of such structures and whether they are simply a curiosity or might they exist in natural systems. To address this, we have created and used numerous chemical approaches. I will discuss the evidence on the existence of G-quadruplexes in human cells and tissues along with our current working hypothesis for what they may be doing in biology. Some of these ideas suggest potential for new therapeutic approaches, especially in oncology.
Speakers
Professor Sir Shankar Balasubramanian
University of Cambridge
United Kingdom
Event details
Dalton Building, Manchester Metropolitan University
Lecture Theatre 1 (G37), Dalton Building, Manchester Metropolitan University, Dalton Building, Chester Street, Manchester, M1 5GD, United Kingdom
Manchester and District