Significant advances in our understanding of the innate immune recognition have been made in the last decade following the identification of three families of pattern recognition receptors: Toll-like receptors (TLRs), NOD-like receptors (NLRs) and RIG-I-like receptors (RLRs). TLRs are pattern recognition receptors that detect motifs or signatures from bacteria, viruses, protozoa and fungi. NLRs detect mainly intracellular bacteria and RLRs detect viral genome. These three families of pattern recognition receptors comprise the front line of defence that the host possesses against microbial pathogens. The aim of this meeting is to provide an overview of these three families of receptors and provide the most recent advances in the area of innate immune pattern recognition.
Chairs: Dr Martha Triantafilou/Dr Kathy Triantafilou, University of Sussex, UK
Chairs: Dr Martha Triantafilou/Dr Kathy Triantafilou, University of Sussex, UK
